P&O Cruises from Southampton

P & O Cruises > P&O Cruises from Southampton

Set sail onboard P&O Cruises from Southampton to a wide range of cruise destinations with specially curated handpicked deals to make sure you are getting the best price possible. Explore the world any time of the year with our summer cruises or winter cruises onboard P&O Cruises state-of-the-art ships. Enjoy fantastic dining options, entertainment and relaxing centres as you sail through different ports of call. Find P&O cruise deals on your P&O Cruises from Southampton sailing and book now for a fraction of the price. 

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Looking for the best cruise deals on P&O cruises from Southampton? Book your cruise deal online or contact us and our expert cruise concierges will help you find the perfect itinerary and best offer on your P&O cruises from Southampton.

Showing 30 out of 357 cruises
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DEPARTS FROM UK

Cruise From:
Was £329pp Now: £319pp

Belgium

Southampton | Zeebrugge | Southampton

  • 05 May 2028
  • 3 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £20pp

Cruise From:
Was £329pp Now: £319pp
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Holiday ID: 098875

DEPARTS FROM UK

Cruise From:
Was £349pp Now: £338pp

France

Southampton | Cherbourg | Le Havre | Southampton

  • 08 Feb 2028
  • 4 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £25pp

Cruise From:
Was £349pp Now: £338pp
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Holiday ID: 098871

DEPARTS FROM UK

Cruise From:
Was £369pp Now: £357pp

Belgium France and Netherlands

Southampton | Zeebrugge | Rotterdam | Cherbourg | Southampton

  • 08 Feb 2027
  • 5 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £369pp Now: £357pp
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Holiday ID: 015060

DEPARTS FROM UK

Cruise From:
Was £369pp Now: £357pp

Rotterdam

Southampton | Rotterdam | Southampton

  • 21 Apr 2027
  • 4 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Multi-Generation Cruise! From toddlers to grandparents, make more holiday memories together
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £127pp

Cruise From:
Was £369pp Now: £357pp
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Holiday ID: 032637

DEPARTS FROM UK

Cruise From:
Was £369pp Now: £357pp

Rotterdam

Southampton | Rotterdam | Southampton

  • 13 Sep 2027
  • 4 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Multi-Generation Cruise! From toddlers to grandparents, make more holiday memories together
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £44pp

Cruise From:
Was £369pp Now: £357pp
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Holiday ID: 032648

DEPARTS FROM UK

Cruise From:
Was £379pp Now: £367pp

Rotterdam

Southampton | Rotterdam | Southampton

  • 26 Feb 2028
  • 4 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £26pp

Cruise From:
Was £379pp Now: £367pp
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Holiday ID: 098874

DEPARTS FROM UK

Cruise From:
Was £389pp Now: £377pp

Belgium France and Netherlands

Southampton | Zeebrugge | Southampton

  • 30 Nov 2026
  • 3 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £389pp Now: £377pp
View cruise
Holiday ID: 015066

DEPARTS FROM UK

Cruise From:
Was £399pp Now: £387pp

Rotterdam

Southampton | Rotterdam | Southampton

  • 21 Jun 2027
  • 4 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Multi-Generation Cruise! From toddlers to grandparents, make more holiday memories together
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £77pp

Cruise From:
Was £399pp Now: £387pp
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Holiday ID: 032640

DEPARTS FROM UK

Cruise From:
Was £419pp Now: £406pp

Belgium and France

Southampton | Zeebrugge | Le Havre | Southampton

  • 29 Nov 2026
  • 4 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £419pp Now: £406pp
View cruise
Holiday ID: 015113

DEPARTS FROM UK

Cruise From:
Was £429pp Now: £416pp

Amsterdam

Southampton | Amsterdam | Southampton

  • 08 Feb 2027
  • 4 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £429pp Now: £416pp
View cruise
Holiday ID: 015115

DEPARTS FROM UK

Cruise From:
Was £429pp Now: £416pp

Belgium

Southampton | Zeebrugge | Southampton

  • 31 Mar 2027
  • 3 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £201pp

Cruise From:
Was £429pp Now: £416pp
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Holiday ID: 032614

DEPARTS FROM UK

Cruise From:
Was £479pp Now: £464pp

Northern European City Escape

Southampton | Rotterdam | Zeebrugge | Hamburg | Southampton

  • 20 Feb 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £479pp Now: £464pp
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Holiday ID: 015062

DEPARTS FROM UK

Cruise From:
Was £499pp Now: £484pp

Rotterdam City Break

Southampton | Rotterdam | Southampton

  • 11 Dec 2026
  • 4 Nights
Multi-Generation Cruise! From toddlers to grandparents, make more holiday memories together
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £499pp Now: £484pp
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Holiday ID: 015121

DEPARTS FROM UK

Cruise From:
Was £499pp Now: £484pp

Amsterdam

Southampton | Amsterdam | Southampton

  • 08 Jun 2027
  • 4 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £107pp

Cruise From:
Was £499pp Now: £484pp
View cruise
Holiday ID: 032621

DEPARTS FROM UK

Cruise From:
Was £499pp Now: £484pp

Belgium And Germany

Southampton | Hamburg | Zeebrugge | Southampton

  • 16 Jul 2027
  • 5 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Multi-Generation Cruise! From toddlers to grandparents, make more holiday memories together
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £81pp

Cruise From:
Was £499pp Now: £484pp
View cruise
Holiday ID: 032643

DEPARTS FROM UK

Cruise From:
Was £499pp Now: £484pp

Spain And France

Southampton | Cherbourg | Vigo | La Coruña | Getxo | Southampton

  • 18 Jan 2027
  • 7 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £499pp Now: £484pp
View cruise
Holiday ID: 035654

DEPARTS FROM UK

Cruise From:
Was £499pp Now: £484pp

Northern European City Escape

Southampton | Zeebrugge | Rotterdam | Hamburg | Southampton

  • 19 Feb 2028
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £35pp

Cruise From:
Was £499pp Now: £484pp
View cruise
Holiday ID: 098873

DEPARTS FROM UK

Cruise From:
Was £529pp Now: £513pp

Northern European City Escape

Southampton | Hamburg | Rotterdam | Zeebrugge | Southampton

  • 31 Oct 2026
  • 7 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £529pp Now: £513pp
View cruise
Holiday ID: 010134

DEPARTS FROM UK

Cruise From:
Was £529pp Now: £513pp

Belgium And Netherlands

Southampton | Rotterdam | Zeebrugge | Southampton

  • 21 Oct 2026
  • 5 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £529pp Now: £513pp
View cruise
Holiday ID: 010147

DEPARTS FROM UK

Cruise From:
Was £539pp Now: £522pp

Amsterdam

Southampton | Amsterdam | Southampton

  • 13 Nov 2026
  • 4 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £539pp Now: £522pp
View cruise
Holiday ID: 015111

DEPARTS FROM UK

Cruise From:
Was £539pp Now: £522pp

Belgium And Netherlands

Southampton | Zeebrugge | Rotterdam | Southampton

  • 27 Aug 2027
  • 5 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Multi-Generation Cruise! From toddlers to grandparents, make more holiday memories together
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £70pp

Cruise From:
Was £539pp Now: £522pp
View cruise
Holiday ID: 032597

DEPARTS FROM UK

Cruise From:
Was £569pp Now: £551pp

PRICE DROP! Northern European City Escape

Southampton | Rotterdam | Zeebrugge | Hamburg | Southampton

  • 13 Feb 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £569pp Now: £551pp
View cruise
Holiday ID: 015061

DEPARTS FROM UK

Cruise From:
Was £569pp Now: £551pp

Amsterdam

Southampton | Amsterdam | Southampton

  • 21 Aug 2027
  • 4 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £76pp

Cruise From:
Was £569pp Now: £551pp
View cruise
Holiday ID: 032629

DEPARTS FROM UK

Cruise From:
Was £579pp Now: £561pp

Spain And France

Southampton | Gijón | La Coruña | Vigo | Cherbourg | Southampton

  • 07 May 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £165pp

Cruise From:
Was £579pp Now: £561pp
View cruise
Holiday ID: 032543

DEPARTS FROM UK

Cruise From:
Was £599pp Now: £581pp

Spain And France

Southampton | Getxo | La Coruña | Vigo | Cherbourg | Southampton

  • 15 Oct 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £63pp

Cruise From:
Was £599pp Now: £581pp
View cruise
Holiday ID: 032613

DEPARTS FROM UK

Cruise From:
Was £599pp Now: £581pp

Belgium And Germany

Southampton | Hamburg | Zeebrugge | Southampton

  • 06 Aug 2027
  • 5 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Multi-Generation Cruise! From toddlers to grandparents, make more holiday memories together
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £86pp

Cruise From:
Was £599pp Now: £581pp
View cruise
Holiday ID: 032645

DEPARTS FROM UK

Cruise From:
Was £599pp Now: £581pp

Spain

Southampton | Vigo | La Coruña | Gijón | Getxo | Southampton

  • 30 Oct 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £59pp

Cruise From:
Was £599pp Now: £581pp
View cruise
Holiday ID: 049324

DEPARTS FROM UK

Cruise From:
Was £609pp Now: £590pp

Spain And France

Southampton | Getxo | La Coruña | Vigo | Cherbourg | Southampton

  • 23 May 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £149pp

Cruise From:
Was £609pp Now: £590pp
View cruise
Holiday ID: 032603

DEPARTS FROM UK

Cruise From:
Was £629pp Now: £610pp

Northern European City Escape

Southampton | Le Havre | Vigo | La Coruña | Getxo | Southampton

  • 17 Oct 2026
  • 7 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £629pp Now: £610pp
View cruise
Holiday ID: 023732

DEPARTS FROM UK

Cruise From:
Was £629pp Now: £610pp

Spain And France

Southampton | Gijón | La Coruña | Vigo | Cherbourg | Southampton

  • 06 Oct 2028
  • 7 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £28pp

Cruise From:
Was £629pp Now: £610pp
View cruise
Holiday ID: 081106

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

Why Choose P&O Cruises From The UK

Southampton is home to the most popular departure port in the UK and is another port for you to explore before or after your cruise. Cruising from Southampton allows you to avoid the fees and hassle of airports to get an early start on your cruises from the UK . P&O cruises from Southampton are perfect for many cruisers since all you have to do is drive down to the port and board your cruise. Whether you are looking for the best cruises for families or venturing out as a couple with our adult only cruises, departing aboard a P&O Cruises from Southampton makes for a more convenient and affordable holiday. Sail hassle free by opting for our all-inclusive cruises. 

P&O Cruises from Southampton destinations 

P&O Cruises from Southampton sails to many amazing destinations. You can sail closer to home on an Europe Cruise and explore popular holiday countries like Spain, France and Portugal or you can see the beauty of the Northern lights on a Norwegian Fjords cruise. If you are looking for warmer climates to escape the cold, the Caribbean is calling with our P&O cruises to the Caribbean, South American Cruises, Mediterranean Cruises, Canaries Islands Cruises and more. P&O cruises from Southampton offers World Cruises where you can explore multiple countries and learn more about the world as you traverse through the continents. Whether you are looking to sail on short break cruises or venturing out with our long duration cruises, you will find P&O cruises from Southampton that will tick all your boxes. 

Book Your P&O Cruises From Southampton

Browse through our wide range of P&O cruises from Southampton with amazing itineraries. Looking to sail a few days or 3 months in the future? Our last minute cruise deals on 2026 cruises will allow you to save more on your cruise holiday. Take advantage of our early booking discounts and save your place onboard with our low deposits when you are sailing on 2027 Cruises or 2028 Cruises. Whenever you are looking to sail, we have exclusive cruise deals on P&O cruises from Southampton.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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