P&O Cruises from Southampton

P & O Cruises > P&O Cruises from Southampton

Set sail onboard P&O Cruises from Southampton to a wide range of cruise destinations with specially curated handpicked deals to make sure you are getting the best price possible. Explore the world any time of the year with our summer cruises or winter cruises onboard P&O Cruises state-of-the-art ships. Enjoy fantastic dining options, entertainment and relaxing centres as you sail through different ports of call. Find P&O cruise deals on your P&O Cruises from Southampton sailing and book now for a fraction of the price. 

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Looking for the best cruise deals on P&O cruises from Southampton? Book your cruise deal online or contact us and our expert cruise concierges will help you find the perfect itinerary and best offer on your P&O cruises from Southampton.

Showing 30 out of 352 cruises
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Fly Cruise From:
Was £1799pp Now: £1745pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Saint Kitts | Castries | Bridgetown | Saint Kitts | Tortola | Sint Maarten | Dominica | Saint John's

  • 22 Oct 2027
  • 22 Nights
  • Arvia
  • Caribbean
  • 22 Oct 2027
  • 22 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £88pp

Fly Cruise From:
Was £1799pp Now: £1745pp
View cruise
REF: POK724C

DEPARTS FROM UK

Cruise From:
Was £699pp Now: £678pp

Spain And France

Southampton | Getxo | La Coruña | Vigo | Cherbourg | Southampton

  • 23 Oct 2027
  • 7 Nights
  • Iona
  • Mediterranean
  • 23 Oct 2027
  • 7 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £34pp

Cruise From:
Was £699pp Now: £678pp
View cruise
REF: POG736

DEPARTS FROM UK

Cruise From:
Was £699pp Now: £678pp

Spain And Portugal

Southampton | Vigo | Lisbon | Leixões | La Coruña | Southampton

  • 23 Oct 2027
  • 7 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £34pp

Cruise From:
Was £699pp Now: £678pp
View cruise
REF: PON727

DEPARTS FROM UK

Cruise From:
Was £1779pp Now: £1725pp

Spain Portugal And Morocco

Southampton | Funchal | Agadir | Casablanca | Tangier | Motril | Lisbon | Southampton

  • 25 Oct 2027
  • 14 Nights
  • Arcadia
  • Mediterranean
  • 25 Oct 2027
  • 14 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £87pp

Cruise From:
Was £1779pp Now: £1725pp
View cruise
REF: POJ715

DEPARTS FROM UK

Cruise From:
Was £2449pp Now: £2375pp

Spain Portugal Cape Verde And Morocco

Southampton | La Coruña | Vigo | Ponta Delgada | Praia da Vitória | Funchal | Praia | Sao Vicente Island | Lanzarote | Agadir | Casablanca | Cádiz | Southampton

  • 25 Oct 2027
  • 23 Nights
  • Aurora
  • Mediterranean
  • 25 Oct 2027
  • 23 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £119pp

Cruise From:
Was £2449pp Now: £2375pp
View cruise
REF: POR720N

DEPARTS FROM UK

Cruise From:
Was £1079pp Now: £1046pp

Spain Madeira And Canary Islands

Southampton | Lanzarote | Las Palmas de Gran Canaria | Santa Cruz de Tenerife | Santa Cruz de La Palma | Funchal | Gibraltar | Cádiz | Southampton

  • 29 Oct 2027
  • 14 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £53pp

Cruise From:
Was £1079pp Now: £1046pp
View cruise
REF: POB728
Fly Cruise From:
Was £1099pp Now: £1066pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Dominica | Bridgetown

  • 30 Oct 2027
  • 14 Nights
  • Iona
  • Caribbean
  • 30 Oct 2027
  • 14 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £54pp

Fly Cruise From:
Was £1099pp Now: £1066pp
View cruise
REF: POG737A
Fly Cruise From:
Was £1299pp Now: £1260pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Dominica | Bridgetown | Saint Kitts

  • 30 Oct 2027
  • 16 Nights
  • Iona
  • Caribbean
  • 30 Oct 2027
  • 16 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £63pp

Fly Cruise From:
Was £1299pp Now: £1260pp
View cruise
REF: POG737B
Fly Cruise From:
Was £1649pp Now: £1599pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Dominica | Bridgetown | Saint Kitts | Tortola | Sint Maarten | Martinique | Saint John's

  • 30 Oct 2027
  • 21 Nights
  • Iona
  • Caribbean
  • 30 Oct 2027
  • 21 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £80pp

Fly Cruise From:
Was £1649pp Now: £1599pp
View cruise
REF: POG737C
Fly Cruise From:
Was £1049pp Now: £1017pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Dominica | Bridgetown

  • 30 Oct 2027
  • 13 Nights
  • Iona
  • Caribbean
  • 30 Oct 2027
  • 13 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £51pp

Fly Cruise From:
Was £1049pp Now: £1017pp
View cruise
REF: POG737N

DEPARTS FROM UK

Cruise From:
Was £579pp Now: £561pp

Spain

Southampton | Vigo | La Coruña | Gijón | Getxo | Southampton

  • 30 Oct 2027
  • 7 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £29pp

Cruise From:
Was £579pp Now: £561pp
View cruise
REF: PON728

DEPARTS FROM UK

Cruise From:
Was £879pp Now: £852pp

Spain And Canary Islands

Southampton | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Fuerteventura | Cádiz | Vigo | La Coruña | Southampton

  • 06 Nov 2027
  • 14 Nights
  • Ventura
  • Mediterranean
  • 06 Nov 2027
  • 14 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £43pp

Cruise From:
Was £879pp Now: £852pp
View cruise
REF: PON729

DEPARTS FROM UK

Cruise From:
Was £749pp Now: £726pp

Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Lisbon | Southampton

  • 08 Nov 2027
  • 12 Nights
  • Arcadia
  • Mediterranean
  • 08 Nov 2027
  • 12 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £37pp

Cruise From:
Was £749pp Now: £726pp
View cruise
REF: POJ716

DEPARTS FROM UK

Cruise From:
Was £479pp Now: £464pp

Belgium And Netherlands

Southampton | Hamburg | Zeebrugge | Southampton

  • 12 Nov 2027
  • 5 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare

Interest free Monthly Payments from JUST £22pp

Cruise From:
Was £479pp Now: £464pp
View cruise
REF: POB729

DEPARTS FROM UK

Cruise From:
Was £829pp Now: £799pp

Spain Madeira And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Cádiz | La Coruña | Southampton

  • 17 Nov 2027
  • 14 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £38pp

Cruise From:
Was £829pp Now: £799pp
View cruise
REF: POB730

DEPARTS FROM UK

Cruise From:
Was £1199pp Now: £1163pp

Norway

Southampton | Åndalsnes | Hammerfest | Alta | Hammerfest | Alta | Tromsø | Haugesund | Southampton

  • 17 Nov 2027
  • 12 Nights
  • Aurora
  • Scandinavia
  • 17 Nov 2027
  • 12 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £56pp

Cruise From:
Was £1199pp Now: £1163pp
View cruise
REF: POR721

DEPARTS FROM UK

Cruise From:
Was £1649pp Now: £1599pp

Eastern Mediterranean Discovery

Southampton | Málaga | Palermo | Piraeus | Kusadasi | Rhodes | Heraklion (Iraklion) | Gibraltar | Southampton

  • 20 Nov 2027
  • 19 Nights
  • Arcadia
  • Mediterranean
  • 20 Nov 2027
  • 19 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £76pp

Cruise From:
Was £1649pp Now: £1599pp
View cruise
REF: POJ717

DEPARTS FROM UK

Cruise From:
Was £829pp Now: £799pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Fuerteventura | Cádiz | Lisbon | Southampton

  • 20 Nov 2027
  • 14 Nights
  • Ventura
  • Mediterranean
  • 20 Nov 2027
  • 14 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £38pp

Cruise From:
Was £829pp Now: £799pp
View cruise
REF: PON730

DEPARTS FROM UK

Cruise From:
Was £999pp Now: £969pp

Azores Portugal And Canary Islands

Southampton | Lisbon | Las Palmas de Gran Canaria | Santa Cruz de Tenerife | Santa Cruz de La Palma | Funchal | Ponta Delgada | Praia da Vitória | Southampton

  • 29 Nov 2027
  • 16 Nights
  • Aurora
  • Mediterranean
  • 29 Nov 2027
  • 16 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £46pp

Cruise From:
Was £999pp Now: £969pp
View cruise
REF: POR722

DEPARTS FROM UK

Cruise From:
Was £549pp Now: £532pp

Northern European City Escape

Southampton | Le Havre | Hamburg | Southampton

  • 01 Dec 2027
  • 6 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare

Interest free Monthly Payments from JUST £26pp

Cruise From:
Was £549pp Now: £532pp
View cruise
REF: POB731

DEPARTS FROM UK

Cruise From:
Was £499pp Now: £484pp

Northern Europe And Scandinavia

Southampton | Copenhagen | Oslo | Skagen | Southampton

  • 04 Dec 2027
  • 7 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £23pp

Cruise From:
Was £499pp Now: £484pp
View cruise
REF: PON731

DEPARTS FROM UK

Cruise From:
Was £749pp Now: £726pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 07 Dec 2027
  • 14 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £35pp

Cruise From:
Was £749pp Now: £726pp
View cruise
REF: POB732

DEPARTS FROM UK

Cruise From:
Was £899pp Now: £872pp

Spain And Morocco

Southampton | Agadir | Casablanca | Tangier | Gibraltar | Cádiz | Southampton

  • 09 Dec 2027
  • 12 Nights
  • Arcadia
  • Mediterranean
  • 09 Dec 2027
  • 12 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £42pp

Cruise From:
Was £899pp Now: £872pp
View cruise
REF: POJ718

DEPARTS FROM UK

Cruise From:
Was £479pp Now: £464pp

Belgium And Netherlands

Southampton | Zeebrugge | Amsterdam | Southampton

  • 11 Dec 2027
  • 5 Nights
  • Ventura
  • United Kingdom
  • 11 Dec 2027
  • 5 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare

Interest free Monthly Payments from JUST £21pp

Cruise From:
Was £479pp Now: £464pp
View cruise
REF: PON732

DEPARTS FROM UK

Cruise From:
Was £1399pp Now: £1357pp

Christmas Scandinavian Escape

Southampton | Copenhagen | Gdynia | Oslo | Hamburg | Zeebrugge | Southampton

  • 15 Dec 2027
  • 14 Nights
  • Aurora
  • Scandinavia
  • 15 Dec 2027
  • 14 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £62pp

Cruise From:
Was £1399pp Now: £1357pp
View cruise
REF: POR723

DEPARTS FROM UK

Cruise From:
Was £379pp Now: £367pp

Belgium And France

Southampton | Zeebrugge | Le Havre | Southampton

  • 16 Dec 2027
  • 4 Nights
  • Ventura
  • United Kingdom
  • 16 Dec 2027
  • 4 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare

Interest free Monthly Payments from JUST £17pp

Cruise From:
Was £379pp Now: £367pp
View cruise
REF: PON733

DEPARTS FROM UK

Cruise From:
Was £429pp Now: £416pp

France

Southampton | Le Havre | Southampton

  • 20 Dec 2027
  • 4 Nights
  • Ventura
  • United Kingdom
  • 20 Dec 2027
  • 4 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare

Interest free Monthly Payments from JUST £19pp

Cruise From:
Was £429pp Now: £416pp
View cruise
REF: PON734

DEPARTS FROM UK

Cruise From:
Was £1499pp Now: £1454pp

Christmas In Spain Madeira And Canary Islands

Southampton | La Coruña | Fuerteventura | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Funchal | Southampton

  • 21 Dec 2027
  • 14 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £66pp

Cruise From:
Was £1499pp Now: £1454pp
View cruise
REF: POB733

DEPARTS FROM UK

Cruise From:
Was £1799pp Now: £1745pp

Christmas In Spain Portugal Canary Islands

Southampton | Vigo | Cádiz | Lanzarote | Santa Cruz de Tenerife | Santa Cruz de La Palma | Las Palmas de Gran Canaria | Lisbon | Southampton

  • 21 Dec 2027
  • 16 Nights
  • Arcadia
  • Mediterranean
  • 21 Dec 2027
  • 16 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £79pp

Cruise From:
Was £1799pp Now: £1745pp
View cruise
REF: POJ719

DEPARTS FROM UK

Cruise From:
Was £699pp Now: £678pp

Christmas Northern European City Escape

Southampton | Hamburg | Cherbourg | Le Havre | Southampton

  • 24 Dec 2027
  • 7 Nights
  • Ventura
  • United Kingdom
  • 24 Dec 2027
  • 7 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £31pp

Cruise From:
Was £699pp Now: £678pp
View cruise
REF: V2143617122114

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

Why Choose P&O Cruises From The UK

Southampton is home to the most popular departure port in the UK and is another port for you to explore before or after your cruise. Cruising from Southampton allows you to avoid the fees and hassle of airports to get an early start on your cruises from the UK . P&O cruises from Southampton are perfect for many cruisers since all you have to do is drive down to the port and board your cruise. Whether you are looking for the best cruises for families or venturing out as a couple with our adult only cruises, departing aboard a P&O Cruises from Southampton makes for a more convenient and affordable holiday. Sail hassle free by opting for our all-inclusive cruises. 

P&O Cruises from Southampton destinations 

P&O Cruises from Southampton sails to many amazing destinations. You can sail closer to home on an Europe Cruise and explore popular holiday countries like Spain, France and Portugal or you can see the beauty of the Northern lights on a Norwegian Fjords cruise. If you are looking for warmer climates to escape the cold, the Caribbean is calling with our P&O cruises to the Caribbean, South American Cruises, Mediterranean Cruises, Canaries Islands Cruises and more. P&O cruises from Southampton offers World Cruises where you can explore multiple countries and learn more about the world as you traverse through the continents. Whether you are looking to sail on short break cruises or venturing out with our long duration cruises, you will find P&O cruises from Southampton that will tick all your boxes. 

Book Your P&O Cruises From Southampton

Browse through our wide range of P&O cruises from Southampton with amazing itineraries. Looking to sail a few days or 3 months in the future? Our last minute cruise deals on2025 cruises will allow you to save more on your cruise holiday. Take advantage of our early booking discounts and save your place onboard with our low deposits when you are sailing on 2026 Cruises or 2027 Cruises. Whenever you are looking to sail, we have exclusive cruise deals on P&O cruises from Southampton.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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