P&O Cruises from Southampton

P & O Cruises > P&O Cruises from Southampton

Set sail onboard P&O Cruises from Southampton to a wide range of cruise destinations with specially curated handpicked deals to make sure you are getting the best price possible. Explore the world any time of the year with our summer cruises or winter cruises onboard P&O Cruises state-of-the-art ships. Enjoy fantastic dining options, entertainment and relaxing centres as you sail through different ports of call. Find P&O cruise deals on your P&O Cruises from Southampton sailing and book now for a fraction of the price. 

P&O Cruises P&O Cruise Deals Cruises from Southampton P&O Cruises 2025 P&O Cruises 2026 P&O Cruises 2027

Looking for the best cruise deals on P&O cruises from Southampton? Book your cruise deal online or contact us and our expert cruise concierges will help you find the perfect itinerary and best offer on your P&O cruises from Southampton.

Showing 30 out of 352 cruises
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DEPARTS FROM UK

Cruise From:
Was £729pp Now: £707pp

New Years Eve In Hamburg

Southampton | Hamburg | Zeebrugge | Southampton

  • 29 Dec 2027
  • 5 Nights
  • Aurora
  • United Kingdom
  • 29 Dec 2027
  • 5 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare

Interest free Monthly Payments from JUST £32pp

Cruise From:
Was £729pp Now: £707pp
View cruise
REF: POR724

DEPARTS FROM UK

Cruise From:
Was £749pp Now: £726pp

New Year Northern Europe And Scandinavia

Southampton | Copenhagen | Oslo | Kristiansand | Southampton

  • 31 Dec 2027
  • 8 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £33pp

Cruise From:
Was £749pp Now: £726pp
View cruise
REF: PON736

DEPARTS FROM UK

Cruise From:
Was £7099pp Now: £6886pp

Epic South America Journey

Southampton | Las Palmas de Gran Canaria | Sao Vicente Island | Recife | Salvador de Bahia | Rio de Janeiro | Santos | Montevideo | Falkland Islands | Punta Arenas | Puerto Montt | San Antonio | Coquimbo | Arica | Callao | Fuerte Amador | Cartagena | Aruba | Curaçao | Saint George's | Bridgetown | Castries | Saint John's | Sint Maarten | Santa Cruz de Tenerife | Southampton

  • 03 Jan 2028
  • 75 Nights
  • Aurora
  • Caribbean
  • 03 Jan 2028
  • 75 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit
Cruise From:
Was £7099pp Now: £6886pp
View cruise
REF: V218118010365

DEPARTS FROM UK

Cruise From:
Was £2599pp Now: £2521pp

Caribbean Winter Warmth

Southampton | Santa Cruz de Tenerife | Bridgetown | Martinique | Castries | Bonaire | Aruba | Saint George's | Saint Vincent | Saint John's | Saint Kitts | Sint Maarten | Tortola | Praia da Vitória | Southampton

  • 04 Jan 2028
  • 35 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £114pp

Cruise From:
Was £2599pp Now: £2521pp
View cruise
REF: V2157818010514
Fly Cruise From:
Was £4879pp Now: £4732pp

Southampton to Auckland

Southampton | Las Palmas de Gran Canaria | Bridgetown | Aruba | Manzanillo | San Diego | San Francisco | Honolulu | Nawiliwili | Apia | Suva | Auckland

  • 06 Jan 2028
  • 41 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £213pp

Fly Cruise From:
Was £4879pp Now: £4732pp
View cruise
REF: POJ801SOUAKL
Fly Cruise From:
Was £4049pp Now: £3927pp

Southampton to San Francisco

Southampton | Las Palmas de Gran Canaria | Bridgetown | Aruba | Manzanillo | San Diego | San Francisco

  • 06 Jan 2028
  • 23 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £177pp

Fly Cruise From:
Was £4049pp Now: £3927pp
View cruise
REF: POJ801SOUSFO

DEPARTS FROM UK

Cruise From:
Was £14699pp Now: £14258pp

Epic World Explorer

Southampton | Las Palmas de Gran Canaria | Bridgetown | Aruba | Manzanillo | San Diego | San Francisco | Honolulu | Nawiliwili | Apia | Suva | Auckland | Tauranga | Wellington | Sydney | Airlie Beach | Cairns | Rabaul | Busan | Nagasaki | Kagoshima | Tokyo | Hong Kong | Manila | Nha Trang | Laem Chabang | Singapore | Port Klang | Colombo | Male | Mauritius | Saint-Denis de la Réunion | Durban | Gqeberha (ex Port Elizabeth) | Cape Town | Walvis Bay | Sao Vicente Island | Santa Cruz de Tenerife | Southampton

  • 06 Jan 2028
  • 124 Nights
  • Arcadia
  • Asia & Indian Ocean
  • 06 Jan 2028
  • 124 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit
Cruise From:
Was £14699pp Now: £14258pp
View cruise
REF: V2133418010999
Fly Cruise From:
Was £6499pp Now: £6299pp

Southampton to Sydney

Southampton | Las Palmas de Gran Canaria | Bridgetown | Aruba | Manzanillo | San Diego | San Francisco | Honolulu | Nawiliwili | Apia | Suva | Auckland | Tauranga | Wellington | Sydney

  • 06 Jan 2028
  • 48 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit
Fly Cruise From:
Was £6499pp Now: £6299pp
View cruise
REF: POJ801SOUSYD

DEPARTS FROM UK

Cruise From:
Was £799pp Now: £775pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Lisbon | Vigo | La Coruña | Southampton

  • 08 Jan 2028
  • 14 Nights
  • Ventura
  • Mediterranean
  • 08 Jan 2028
  • 14 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £35pp

Cruise From:
Was £799pp Now: £775pp
View cruise
REF: V2143618010428

DEPARTS FROM UK

Cruise From:
Was £299pp Now: £290pp

Belgium and The Netherlands

Southampton | Zeebrugge | Southampton

  • 22 Jan 2028
  • 3 Nights
  • Ventura
  • United Kingdom
  • 22 Jan 2028
  • 3 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare

Interest free Monthly Payments from JUST £13pp

Cruise From:
Was £299pp Now: £290pp
View cruise
REF: V214361802014

DEPARTS FROM UK

Cruise From:
Was £799pp Now: £775pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 25 Jan 2028
  • 14 Nights
  • Ventura
  • Mediterranean
  • 25 Jan 2028
  • 14 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £34pp

Cruise From:
Was £799pp Now: £775pp
View cruise
REF: V2143618020535

DEPARTS FROM UK

Cruise From:
Was £1099pp Now: £1066pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 08 Feb 2028
  • 14 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £46pp

Cruise From:
Was £1099pp Now: £1066pp
View cruise
REF: V2157818011914

DEPARTS FROM UK

Cruise From:
Was £479pp Now: £464pp

Caribbean

Southampton | Cherbourg | Le Havre | Zeebrugge | Southampton

  • 22 Feb 2028
  • 5 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare

Interest free Monthly Payments from JUST £19pp

Cruise From:
Was £479pp Now: £464pp
View cruise
REF: V2157818020214

DEPARTS FROM UK

Cruise From:
Was £2029pp Now: £1968pp

From Barbados to Barbados

Southampton | Tangier | La Goulette | Valletta | Piraeus | Istanbul | Messina | Cádiz | Southampton

  • 27 Feb 2028
  • 21 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £81pp

Cruise From:
Was £2029pp Now: £1968pp
View cruise
REF: V2157818021614

DEPARTS FROM UK

Cruise From:
Was £299pp Now: £290pp

Canary Islands and Portugal

Southampton | Zeebrugge | Southampton

  • 27 Feb 2028
  • 3 Nights
  • Ventura
  • United Kingdom
  • 27 Feb 2028
  • 3 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare

Interest free Monthly Payments from JUST £12pp

Cruise From:
Was £299pp Now: £290pp
View cruise
REF: V2143618032812

DEPARTS FROM UK

Cruise From:
Was £1099pp Now: £1066pp

Spain and Portugal

Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Lisbon | Vigo | La Coruña | Southampton

  • 01 Mar 2028
  • 14 Nights
  • Ventura
  • Mediterranean
  • 01 Mar 2028
  • 14 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £44pp

Cruise From:
Was £1099pp Now: £1066pp
View cruise
REF: V2143618040912

DEPARTS FROM UK

Cruise From:
Was £299pp Now: £290pp

Portugal and Canary Islands

Southampton | Zeebrugge | Southampton

  • 15 Mar 2028
  • 3 Nights
  • Ventura
  • United Kingdom
  • 15 Mar 2028
  • 3 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare

Interest free Monthly Payments from JUST £12pp

Cruise From:
Was £299pp Now: £290pp
View cruise
REF: V2143618042113

DEPARTS FROM UK

Cruise From:
Was £629pp Now: £610pp

Spain, Portugal and Guernsey

Southampton | Copenhagen | Oslo | Kristiansand | Southampton

  • 18 Mar 2028
  • 7 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £24pp

Cruise From:
Was £629pp Now: £610pp
View cruise
REF: V214361805047

DEPARTS FROM UK

Cruise From:
Was £1079pp Now: £1046pp

Norway and Northern Lights

Southampton | Åndalsnes | Bodø | Tromsø | Haugesund | Southampton

  • 18 Mar 2028
  • 12 Nights
  • Aurora
  • Scandinavia
  • 18 Mar 2028
  • 12 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £41pp

Cruise From:
Was £1079pp Now: £1046pp
View cruise
REF: V218118030912

DEPARTS FROM UK

Cruise From:
Was £1099pp Now: £1066pp

Caribbean

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Lanzarote | Cádiz | Lisbon | Southampton

  • 19 Mar 2028
  • 14 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £42pp

Cruise From:
Was £1099pp Now: £1066pp
View cruise
REF: V2157818030214

DEPARTS FROM UK

Cruise From:
Was £599pp Now: £581pp

Spain, France and Italy

Southampton | Bremerhaven | Amsterdam | Zeebrugge | Le Havre | Southampton

  • 25 Mar 2028
  • 7 Nights
  • Ventura
  • United Kingdom
  • 25 Mar 2028
  • 7 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £23pp

Cruise From:
Was £599pp Now: £581pp
View cruise
REF: V2143618051114

DEPARTS FROM UK

Cruise From:
Was £1079pp Now: £1046pp

Portugal, Caribbean and Azores

Southampton | Åndalsnes | Alta | Tromsø | Haugesund | Southampton

  • 30 Mar 2028
  • 12 Nights
  • Aurora
  • Scandinavia
  • 30 Mar 2028
  • 12 Nights
Black Friday Sale! Save up to £300 per cabin - Book by 2nd December
Winter 2027/28 now on sale! 10% early booking discount when you book a select fare
Extra on-board spending money, 20% off Classic Drinks packages and just 10% deposit

Interest free Monthly Payments from JUST £41pp

Cruise From:
Was £1079pp Now: £1046pp
View cruise
REF: V218118032125

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

Why Choose P&O Cruises From The UK

Southampton is home to the most popular departure port in the UK and is another port for you to explore before or after your cruise. Cruising from Southampton allows you to avoid the fees and hassle of airports to get an early start on your cruises from the UK . P&O cruises from Southampton are perfect for many cruisers since all you have to do is drive down to the port and board your cruise. Whether you are looking for the best cruises for families or venturing out as a couple with our adult only cruises, departing aboard a P&O Cruises from Southampton makes for a more convenient and affordable holiday. Sail hassle free by opting for our all-inclusive cruises. 

P&O Cruises from Southampton destinations 

P&O Cruises from Southampton sails to many amazing destinations. You can sail closer to home on an Europe Cruise and explore popular holiday countries like Spain, France and Portugal or you can see the beauty of the Northern lights on a Norwegian Fjords cruise. If you are looking for warmer climates to escape the cold, the Caribbean is calling with our P&O cruises to the Caribbean, South American Cruises, Mediterranean Cruises, Canaries Islands Cruises and more. P&O cruises from Southampton offers World Cruises where you can explore multiple countries and learn more about the world as you traverse through the continents. Whether you are looking to sail on short break cruises or venturing out with our long duration cruises, you will find P&O cruises from Southampton that will tick all your boxes. 

Book Your P&O Cruises From Southampton

Browse through our wide range of P&O cruises from Southampton with amazing itineraries. Looking to sail a few days or 3 months in the future? Our last minute cruise deals on2025 cruises will allow you to save more on your cruise holiday. Take advantage of our early booking discounts and save your place onboard with our low deposits when you are sailing on 2026 Cruises or 2027 Cruises. Whenever you are looking to sail, we have exclusive cruise deals on P&O cruises from Southampton.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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