P&O Cruises from Southampton

P & O Cruises > P&O Cruises from Southampton

Set sail onboard P&O Cruises from Southampton to a wide range of cruise destinations with specially curated handpicked deals to make sure you are getting the best price possible. Explore the world any time of the year with our summer cruises or winter cruises onboard P&O Cruises state-of-the-art ships. Enjoy fantastic dining options, entertainment and relaxing centres as you sail through different ports of call. Find P&O cruise deals on your P&O Cruises from Southampton sailing and book now for a fraction of the price. 

P&O Cruises P&O Cruise Deals  P&O Cruises 2026 P&O Cruises 2027 P&O Cruises 2028

Looking for the best cruise deals on P&O cruises from Southampton? Book your cruise deal online or contact us and our expert cruise concierges will help you find the perfect itinerary and best offer on your P&O cruises from Southampton.

Showing 30 out of 384 cruises
Per Person
Total Price
List Grid

Range:

APPLY

DEPARTS FROM UK

Cruise From:
Was £6499pp Now: £6299pp

America and Caribbean Discovery

Southampton | Funchal | Sint Maarten | Saint John's | Dominica | Saint Vincent | Saint George's | Port-of-Spain | Bonaire | Curaçao | Cartagena | Colón | Puerto Limón | Roatán Island | Costa Maya | Grand Cayman | Cozumel | Progreso | Galveston | New Orleans | Miami | Port Canaveral | Freeport | Grand Turk Island | Amber Cove | Ocho Rios | Falmouth | Tortola | Saint Kitts | Guadeloupe | Martinique | Castries | Scarborough | Bridgetown | Praia da Vitória | Southampton

  • 03 Jan 2027
  • 75 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £6499pp Now: £6299pp
View cruise
Holiday ID: 015124

DEPARTS FROM UK

Cruise From:
Was £2999pp Now: £2899pp

Caribbean Discovery

Southampton | Santa Cruz de Tenerife | Saint Kitts | Bridgetown | Saint George's | Castries | Sint Maarten | Saint John's | Las Palmas de Gran Canaria | La Coruña | Southampton

  • 04 Jan 2027
  • 35 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £2999pp Now: £2899pp
View cruise
Holiday ID: 015059

DEPARTS FROM UK

Cruise From:
Was £949pp Now: £920pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 04 Jan 2027
  • 14 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £949pp Now: £920pp
View cruise
Holiday ID: 035653
Fly Cruise From:
Was £6999pp Now: £6789pp

World Cruise Segment - Southampton to Brisbane

Southampton | Funchal | Bridgetown | Curaçao | Manzanillo | San Francisco | Hilo | Honolulu | Apia | Suva | Port Vila | Sydney | Newcastle | Brisbane

  • 06 Jan 2027
  • 48 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Fly Cruise From:
Was £6999pp Now: £6789pp
View cruise
Holiday ID: 015074
Fly Cruise From:
Was £2699pp Now: £2618pp

World Cruise Segment - Southampton to San Francisco

Southampton | Funchal | Bridgetown | Curaçao | Manzanillo | San Francisco

  • 06 Jan 2027
  • 22 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Fly Cruise From:
Was £2699pp Now: £2618pp
View cruise
Holiday ID: 015075

DEPARTS FROM UK

Cruise From:
Was £12999pp Now: £12599pp

Western Circumnavigation

Southampton | Funchal | Bridgetown | Curaçao | Manzanillo | San Francisco | Hilo | Honolulu | Apia | Suva | Port Vila | Sydney | Newcastle | Brisbane | Cairns | Alotau | Manila | Hong Kong | Singapore | Port Klang | Georgetown | Colombo | Mauritius | Saint-Denis de la Réunion | Durban | Gqeberha (ex Port Elizabeth) | Cape Town | Walvis Bay | Sao Vicente Island | Santa Cruz de Tenerife | Southampton

  • 06 Jan 2027
  • 107 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £12999pp Now: £12599pp
View cruise
Holiday ID: 015076
Fly Cruise From:
Was £14809pp Now: £14364pp

World Cruise Segment - Southampton to Sydney

Southampton | Funchal | Bridgetown | Curaçao | Manzanillo | San Francisco | Hilo | Honolulu | Apia | Suva | Port Vila | Sydney

  • 06 Jan 2027
  • 43 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Fly Cruise From:
Was £14809pp Now: £14364pp
View cruise
Holiday ID: 015077
Fly Cruise From:
Was £6679pp Now: £6478pp

Epic World Explorer

Southampton | Funchal | Bridgetown | Curaçao | Manzanillo | San Francisco | Hilo | Honolulu | Apia | Suva | Port Vila | Sydney | Newcastle | Brisbane | Cairns | Alotau | Manila | Hong Kong

  • 06 Jan 2027
  • 63 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Fly Cruise From:
Was £6679pp Now: £6478pp
View cruise
Holiday ID: 041430

DEPARTS FROM UK

Cruise From:
Was £499pp Now: £484pp

Spain And France

Southampton | Cherbourg | Vigo | La Coruña | Getxo | Southampton

  • 18 Jan 2027
  • 7 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £499pp Now: £484pp
View cruise
Holiday ID: 035654

DEPARTS FROM UK

Cruise From:
Was £899pp Now: £872pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 25 Jan 2027
  • 14 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £899pp Now: £872pp
View cruise
Holiday ID: 035655

DEPARTS FROM UK

Cruise From:
Was £369pp Now: £357pp

Belgium France and Netherlands

Southampton | Zeebrugge | Rotterdam | Cherbourg | Southampton

  • 08 Feb 2027
  • 5 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £369pp Now: £357pp
View cruise
Holiday ID: 015060

DEPARTS FROM UK

Cruise From:
Was £429pp Now: £416pp

Amsterdam

Southampton | Amsterdam | Southampton

  • 08 Feb 2027
  • 4 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £429pp Now: £416pp
View cruise
Holiday ID: 015115

DEPARTS FROM UK

Cruise From:
Was £1099pp Now: £1066pp

Spain Portugal Canary Islands and Morocco

Southampton | Funchal | Santa Cruz de La Palma | Las Palmas de Gran Canaria | Casablanca | Tangier | Cádiz | La Coruña | Southampton

  • 12 Feb 2027
  • 14 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £1099pp Now: £1066pp
View cruise
Holiday ID: 015116

DEPARTS FROM UK

Cruise From:
Was £569pp Now: £551pp

PRICE DROP! Northern European City Escape

Southampton | Rotterdam | Zeebrugge | Hamburg | Southampton

  • 13 Feb 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £569pp Now: £551pp
View cruise
Holiday ID: 015061

DEPARTS FROM UK

Cruise From:
Was £479pp Now: £464pp

Northern European City Escape

Southampton | Rotterdam | Zeebrugge | Hamburg | Southampton

  • 20 Feb 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £479pp Now: £464pp
View cruise
Holiday ID: 015062

DEPARTS FROM UK

Cruise From:
Was £1549pp Now: £1499pp

Central Mediterranean Discovery

Southampton | Cartagena | La Goulette | Valletta | Piraeus | Naples | Civitavecchia | Barcelona | Alicante | Cádiz | Lisbon | Southampton

  • 26 Feb 2027
  • 21 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £1549pp Now: £1499pp
View cruise
Holiday ID: 015117

DEPARTS FROM UK

Cruise From:
Was £949pp Now: £920pp

Spain Portugal and Canary Islands

Southampton | Funchal | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 27 Feb 2027
  • 14 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £949pp Now: £920pp
View cruise
Holiday ID: 015063

DEPARTS FROM UK

Cruise From:
Was £899pp Now: £872pp

Spain Portugal and Canary Islands

Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Lisbon | Vigo | La Coruña | Southampton

  • 13 Mar 2027
  • 14 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £899pp Now: £872pp
View cruise
Holiday ID: 015064

DEPARTS FROM UK

Cruise From:
Was £799pp Now: £775pp

Portugal and Canary Islands

Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Lisbon | Southampton

  • 19 Mar 2027
  • 12 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £799pp Now: £775pp
View cruise
Holiday ID: 015118

DEPARTS FROM UK

Cruise From:
Was £1549pp Now: £1499pp

Norway

Southampton | Ålesund | Bodø | Narvik | Tromsø | Haugesund | Southampton

  • 19 Mar 2027
  • 14 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £1549pp Now: £1499pp
View cruise
Holiday ID: 015125

DEPARTS FROM UK

Cruise From:
Was £679pp Now: £658pp

PRICE DROP! Northern European City Escape

Southampton | Hamburg | Rotterdam | Zeebrugge | Southampton

  • 27 Mar 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £679pp Now: £658pp
View cruise
Holiday ID: 015065

DEPARTS FROM UK

Cruise From:
Was £969pp Now: £939pp

PRICE DROP! Norwegian Fjords

Southampton | Haugesund | Olden | Ålesund | Stavanger | Southampton

  • 28 Mar 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £969pp Now: £939pp
View cruise
Holiday ID: 035646

DEPARTS FROM UK

Cruise From:
Was £429pp Now: £416pp

Belgium

Southampton | Zeebrugge | Southampton

  • 31 Mar 2027
  • 3 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £205pp

Cruise From:
Was £429pp Now: £416pp
View cruise
Holiday ID: 032614

DEPARTS FROM UK

Cruise From:
Was £1649pp Now: £1599pp

Eastern Mediterranean Discovery

Southampton | Cádiz | Heraklion (Iraklion) | Alexandria | La Goulette | Cartagena | Tangier | Ferrol | Southampton

  • 02 Apr 2027
  • 19 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £1649pp Now: £1599pp
View cruise
Holiday ID: 032636

DEPARTS FROM UK

Cruise From:
Was £1349pp Now: £1299pp

Spain France And Norwegian Fjords

Southampton | Gijón | La Coruña | Vigo | Cherbourg | Southampton | Haugesund | Ålesund | Skjolden | Stavanger | Southampton

  • 02 Apr 2027
  • 14 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £1349pp Now: £1299pp
View cruise
Holiday ID: 074823

DEPARTS FROM UK

Cruise From:
Was £699pp Now: £678pp

Spain And France

Southampton | Gijón | La Coruña | Vigo | Cherbourg | Southampton

  • 02 Apr 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £699pp Now: £678pp
View cruise
Holiday ID: 074824

DEPARTS FROM UK

Cruise From:
Was £819pp Now: £794pp

PRICE DROP! Norwegian Fjords

Southampton | Stavanger | Olden | Ålesund | Haugesund | Southampton

  • 03 Apr 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £819pp Now: £794pp
View cruise
Holiday ID: 032561

DEPARTS FROM UK

Cruise From:
Was £949pp Now: £920pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 03 Apr 2027
  • 14 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £949pp Now: £920pp
View cruise
Holiday ID: 032615

DEPARTS FROM UK

Cruise From:
Was £749pp Now: £726pp

PRICE DROP! Norwegian Fjords

Southampton | Haugesund | Olden | Ålesund | Stavanger | Southampton

  • 04 Apr 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £749pp Now: £726pp
View cruise
Holiday ID: 035647

DEPARTS FROM UK

Cruise From:
Was £679pp Now: £658pp

Norwegian Fjords

Southampton | Haugesund | Ålesund | Skjolden | Stavanger | Southampton

  • 09 Apr 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £679pp Now: £658pp
View cruise
Holiday ID: 074825

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

Why Choose P&O Cruises From The UK

Southampton is home to the most popular departure port in the UK and is another port for you to explore before or after your cruise. Cruising from Southampton allows you to avoid the fees and hassle of airports to get an early start on your cruises from the UK . P&O cruises from Southampton are perfect for many cruisers since all you have to do is drive down to the port and board your cruise. Whether you are looking for the best cruises for families or venturing out as a couple with our adult only cruises, departing aboard a P&O Cruises from Southampton makes for a more convenient and affordable holiday. Sail hassle free by opting for our all-inclusive cruises. 

P&O Cruises from Southampton destinations 

P&O Cruises from Southampton sails to many amazing destinations. You can sail closer to home on an Europe Cruise and explore popular holiday countries like Spain, France and Portugal or you can see the beauty of the Northern lights on a Norwegian Fjords cruise. If you are looking for warmer climates to escape the cold, the Caribbean is calling with our P&O cruises to the Caribbean, South American Cruises, Mediterranean Cruises, Canaries Islands Cruises and more. P&O cruises from Southampton offers World Cruises where you can explore multiple countries and learn more about the world as you traverse through the continents. Whether you are looking to sail on short break cruises or venturing out with our long duration cruises, you will find P&O cruises from Southampton that will tick all your boxes. 

Book Your P&O Cruises From Southampton

Browse through our wide range of P&O cruises from Southampton with amazing itineraries. Looking to sail a few days or 3 months in the future? Our last minute cruise deals on 2026 cruises will allow you to save more on your cruise holiday. Take advantage of our early booking discounts and save your place onboard with our low deposits when you are sailing on 2027 Cruises or 2028 Cruises. Whenever you are looking to sail, we have exclusive cruise deals on P&O cruises from Southampton.

Our Award Winning Service

Good Housekeeping Reader Recommended 2026
Good Housekeeping Reader Recommended 2026
Best Workplaces in Travel 2026
Best Workplaces in Travel 2026
UK Cruise Awards 2026 Partnership Achievement Award awards
UK Cruise Awards 2026 Partnership Achievement Award
Best Workplaces in Travel 2024 awards
Best Workplaces in Travel 2024
Travel Weekly Travel Agent Award 2023 awards
Travel Weekly Travel Agent Award 2023
Best Online Travel Agency 2022 awards
Best Online Travel Agency 2022
TTG Top 50 Ocean Travel Agency 2022 awards
TTG Top 50 Ocean Travel Agency 2022
Best Online Agent 2021 awards
Best Online Agent 2021
Best Company 2020 awards
Best Company 2020
Best Online Agent 2019 awards
Best Online Agent 2019
TTG Top 50 Travel Agency 2019 awards
TTG Top 50 Travel Agency 2019
Explore
Blog
About Us
Careers
Contact Us
Cruise118.com Brochures
Frequently Asked Questions
Privacy Policy
Terms and Conditions
Marketing Preferences
Modern Slavery Statement
Cruise Deals
Cruise Deals
Fly Cruise Deals
2026 Cruises
2027 Cruises
All Inclusive Deals
Last Minute Cruise Deals
Cheap Cruise Deals
Family Cruises
Short Cruises
Adult Only Cruises
Cruise Lines
Ambassador Cruise Line
Celebrity Cruises
Disney Cruise Line
Fred Olsen Cruise Lines
MSC Cruises
Norwegian Cruise Line
P&O Cruises
Princess Cruises
Royal Caribbean International
Virgin Voyages
All Cruise Lines
Popular Ships
Celebrity Apex
MSC Virtuosa
MSC Euribia
MSC World Europa
Arvia
Britannia
Iona
Sky Princess
Icon of The Seas
Destinations
Caribbean
Italy
Mediterranean
South America
United Kingdom
All Destinations
Cyber Essentials Plus logo ABTA member
follow us
World Travel Holdings
This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
You've added to your wishlist. To view, go to Wishlist
Call for Free