P&O Cruises from Southampton

P & O Cruises > P&O Cruises from Southampton

Set sail onboard P&O Cruises from Southampton to a wide range of cruise destinations with specially curated handpicked deals to make sure you are getting the best price possible. Explore the world any time of the year with our summer cruises or winter cruises onboard P&O Cruises state-of-the-art ships. Enjoy fantastic dining options, entertainment and relaxing centres as you sail through different ports of call. Find P&O cruise deals on your P&O Cruises from Southampton sailing and book now for a fraction of the price. 

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Looking for the best cruise deals on P&O cruises from Southampton? Book your cruise deal online or contact us and our expert cruise concierges will help you find the perfect itinerary and best offer on your P&O cruises from Southampton.

Showing 30 out of 385 cruises
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DEPARTS FROM UK

Cruise From:
Was £1949pp Now: £1890pp

Western Mediterranean Discovery

Southampton | Lisbon | Alicante | Livorno | Civitavecchia | Cartagena | Casablanca | Tangier | Vigo | Southampton

  • 01 Sep 2027
  • 19 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £243pp

Cruise From:
Was £1949pp Now: £1890pp
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Holiday ID: 032598

DEPARTS FROM UK

Cruise From:
Was £1149pp Now: £1114pp

Norwegian Fjords

Southampton | Skjolden | Nordfjordeid | Kristiansund | Åndalsnes | Ålesund | Eidfjord | Zeebrugge | Southampton

  • 01 Sep 2027
  • 12 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £144pp

Cruise From:
Was £1149pp Now: £1114pp
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Holiday ID: 032647

DEPARTS FROM UK

Cruise From:
Was £729pp Now: £707pp

Norwegian Fjords

Southampton | Stavanger | Ålesund | Olden | Haugesund | Southampton

  • 04 Sep 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £90pp

Cruise From:
Was £729pp Now: £707pp
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Holiday ID: 032583

DEPARTS FROM UK

Cruise From:
Was £1449pp Now: £1399pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 04 Sep 2027
  • 14 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £178pp

Cruise From:
Was £1449pp Now: £1399pp
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Holiday ID: 032631

DEPARTS FROM UK

Cruise From:
Was £679pp Now: £658pp

Norwegian Fjords

Southampton | Skjolden | Ålesund | Stavanger | Southampton

  • 05 Sep 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £84pp

Cruise From:
Was £679pp Now: £658pp
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Holiday ID: 035651

DEPARTS FROM UK

Cruise From:
Was £729pp Now: £707pp

Norwegian Fjords

Southampton | Stavanger | Olden | Haugesund | Kristiansand | Southampton

  • 10 Sep 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £88pp

Cruise From:
Was £729pp Now: £707pp
View cruise
Holiday ID: 032556

DEPARTS FROM UK

Cruise From:
Was £679pp Now: £658pp

Norwegian Fjords

Southampton | Stavanger | Ålesund | Olden | Haugesund | Southampton

  • 11 Sep 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £81pp

Cruise From:
Was £679pp Now: £658pp
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Holiday ID: 032584

DEPARTS FROM UK

Cruise From:
Was £1529pp Now: £1483pp

Mediterranean - Spain France And Italy

Southampton | Cádiz | Barcelona | La Seyne-sur-Mer | La Spezia | Civitavecchia | Alicante | Southampton

  • 12 Sep 2027
  • 14 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £182pp

Cruise From:
Was £1529pp Now: £1483pp
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Holiday ID: 032612

DEPARTS FROM UK

Cruise From:
Was £369pp Now: £357pp

Rotterdam

Southampton | Rotterdam | Southampton

  • 13 Sep 2027
  • 4 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Multi-Generation Cruise! From toddlers to grandparents, make more holiday memories together
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £44pp

Cruise From:
Was £369pp Now: £357pp
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Holiday ID: 032648

DEPARTS FROM UK

Cruise From:
Was £729pp Now: £707pp

Norwegian Fjords

Southampton | Haugesund | Olden | Ålesund | Stavanger | Southampton

  • 17 Sep 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £85pp

Cruise From:
Was £729pp Now: £707pp
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Holiday ID: 032557

DEPARTS FROM UK

Cruise From:
Was £3499pp Now: £3394pp

Canadian Wonders

Southampton | Saint-John's | Gaspé | Havre-Saint-Pierre | Quebec City | Saguenay | Charlottetown | Magdalen Islands | Halifax | Sydney | Southampton

  • 17 Sep 2027
  • 24 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £3499pp Now: £3394pp
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Holiday ID: 032688

DEPARTS FROM UK

Cruise From:
Was £679pp Now: £658pp

Norwegian Fjords

Southampton | Kristiansand | Stavanger | Olden | Haugesund | Southampton

  • 18 Sep 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £79pp

Cruise From:
Was £679pp Now: £658pp
View cruise
Holiday ID: 032585

DEPARTS FROM UK

Cruise From:
Was £1429pp Now: £1386pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | La Coruña | Southampton

  • 18 Sep 2027
  • 14 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £166pp

Cruise From:
Was £1429pp Now: £1386pp
View cruise
Holiday ID: 032632

DEPARTS FROM UK

Cruise From:
Was £1349pp Now: £1299pp

Norwegian Fjords

Southampton | Kristiansand | Olden | Ålesund | Bodø | Åndalsnes | Bergen | Zeebrugge | Southampton

  • 20 Sep 2027
  • 14 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Multi-Generation Cruise! From toddlers to grandparents, make more holiday memories together
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £154pp

Cruise From:
Was £1349pp Now: £1299pp
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Holiday ID: 032599

DEPARTS FROM UK

Cruise From:
Was £2079pp Now: £2016pp

Northern Europe And Scandinavia

Southampton | Kiel | Tallinn | Helsinki | Stockholm | Copenhagen | Skagen | Southampton

  • 24 Sep 2027
  • 14 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £235pp

Cruise From:
Was £2079pp Now: £2016pp
View cruise
Holiday ID: 032558

DEPARTS FROM UK

Cruise From:
Was £699pp Now: £678pp

Norwegian Fjords

Southampton | Stavanger | Ålesund | Olden | Haugesund | Southampton

  • 25 Sep 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £79pp

Cruise From:
Was £699pp Now: £678pp
View cruise
Holiday ID: 032586

DEPARTS FROM UK

Cruise From:
Was £1349pp Now: £1299pp

Spain Portugal And Canary Islands

Southampton | Lanzarote | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Funchal | Cádiz | Lisbon | Southampton

  • 02 Oct 2027
  • 14 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £147pp

Cruise From:
Was £1349pp Now: £1299pp
View cruise
Holiday ID: 032587

DEPARTS FROM UK

Cruise From:
Was £739pp Now: £716pp

Spain France And Portugal

Southampton | Vigo | Lisbon | Leixões | Cherbourg | Southampton

  • 02 Oct 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £81pp

Cruise From:
Was £739pp Now: £716pp
View cruise
Holiday ID: 032633

DEPARTS FROM UK

Cruise From:
Was £3999pp Now: £3879pp

Central Mediterranean Discovery

Southampton | Cartagena | La Goulette | Palermo | Sarandë | Dubrovnik | Split | Zadar | Korčula | Valletta | Cádiz | Southampton

  • 04 Oct 2027
  • 21 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £3999pp Now: £3879pp
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Holiday ID: 032600

DEPARTS FROM UK

Cruise From:
Was £639pp Now: £619pp

Spain And France

Southampton | Gijón | La Coruña | Vigo | Cherbourg | Southampton

  • 08 Oct 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £68pp

Cruise From:
Was £639pp Now: £619pp
View cruise
Holiday ID: 032559

DEPARTS FROM UK

Cruise From:
Was £1149pp Now: £1114pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 09 Oct 2027
  • 14 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £122pp

Cruise From:
Was £1149pp Now: £1114pp
View cruise
Holiday ID: 032634

DEPARTS FROM UK

Cruise From:
Was £1229pp Now: £1192pp

Norwegian Fjords

Southampton | Haugesund | Olden | Molde | Bodø | Ålesund | Skjolden | Stavanger | Southampton

  • 11 Oct 2027
  • 14 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £130pp

Cruise From:
Was £1229pp Now: £1192pp
View cruise
Holiday ID: 032649

DEPARTS FROM UK

Cruise From:
Was £1299pp Now: £1260pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Ferrol | Southampton

  • 15 Oct 2027
  • 14 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £135pp

Cruise From:
Was £1299pp Now: £1260pp
View cruise
Holiday ID: 032560

DEPARTS FROM UK

Cruise From:
Was £599pp Now: £581pp

Spain And France

Southampton | Getxo | La Coruña | Vigo | Cherbourg | Southampton

  • 15 Oct 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £63pp

Cruise From:
Was £599pp Now: £581pp
View cruise
Holiday ID: 032613

DEPARTS FROM UK

Cruise From:
Was £679pp Now: £658pp

Northern European City Escape

Southampton | Zeebrugge | Rotterdam | Hamburg | Southampton

  • 16 Oct 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £70pp

Cruise From:
Was £679pp Now: £658pp
View cruise
Holiday ID: 032588
Fly Cruise From:
Was £1099pp Now: £1066pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Saint Kitts | Castries | Bridgetown

  • 22 Oct 2027
  • 14 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £111pp

Fly Cruise From:
Was £1099pp Now: £1066pp
View cruise
Holiday ID: 049282
Fly Cruise From:
Was £1129pp Now: £1095pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Saint Kitts | Castries | Bridgetown

  • 22 Oct 2027
  • 15 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £114pp

Fly Cruise From:
Was £1129pp Now: £1095pp
View cruise
Holiday ID: 049283
Fly Cruise From:
Was £1399pp Now: £1357pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Saint Kitts | Castries | Bridgetown | Saint Kitts

  • 22 Oct 2027
  • 17 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £141pp

Fly Cruise From:
Was £1399pp Now: £1357pp
View cruise
Holiday ID: 049284
Fly Cruise From:
Was £1879pp Now: £1822pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Saint Kitts | Castries | Bridgetown | Saint Kitts | Tortola | Sint Maarten | Dominica | Saint John's

  • 22 Oct 2027
  • 22 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £190pp

Fly Cruise From:
Was £1879pp Now: £1822pp
View cruise
Holiday ID: 049285

DEPARTS FROM UK

Cruise From:
Was £649pp Now: £629pp

PRICE DROP! Spain And France

Southampton | Cherbourg | Getxo | La Coruña | Vigo | Southampton

  • 23 Oct 2027
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £66pp

Cruise From:
Was £649pp Now: £629pp
View cruise
Holiday ID: 032589

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

Why Choose P&O Cruises From The UK

Southampton is home to the most popular departure port in the UK and is another port for you to explore before or after your cruise. Cruising from Southampton allows you to avoid the fees and hassle of airports to get an early start on your cruises from the UK . P&O cruises from Southampton are perfect for many cruisers since all you have to do is drive down to the port and board your cruise. Whether you are looking for the best cruises for families or venturing out as a couple with our adult only cruises, departing aboard a P&O Cruises from Southampton makes for a more convenient and affordable holiday. Sail hassle free by opting for our all-inclusive cruises. 

P&O Cruises from Southampton destinations 

P&O Cruises from Southampton sails to many amazing destinations. You can sail closer to home on an Europe Cruise and explore popular holiday countries like Spain, France and Portugal or you can see the beauty of the Northern lights on a Norwegian Fjords cruise. If you are looking for warmer climates to escape the cold, the Caribbean is calling with our P&O cruises to the Caribbean, South American Cruises, Mediterranean Cruises, Canaries Islands Cruises and more. P&O cruises from Southampton offers World Cruises where you can explore multiple countries and learn more about the world as you traverse through the continents. Whether you are looking to sail on short break cruises or venturing out with our long duration cruises, you will find P&O cruises from Southampton that will tick all your boxes. 

Book Your P&O Cruises From Southampton

Browse through our wide range of P&O cruises from Southampton with amazing itineraries. Looking to sail a few days or 3 months in the future? Our last minute cruise deals on 2026 cruises will allow you to save more on your cruise holiday. Take advantage of our early booking discounts and save your place onboard with our low deposits when you are sailing on 2027 Cruises or 2028 Cruises. Whenever you are looking to sail, we have exclusive cruise deals on P&O cruises from Southampton.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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