P&O Cruises from Southampton

P & O Cruises > P&O Cruises from Southampton

Set sail onboard P&O Cruises from Southampton to a wide range of cruise destinations with specially curated handpicked deals to make sure you are getting the best price possible. Explore the world any time of the year with our summer cruises or winter cruises onboard P&O Cruises state-of-the-art ships. Enjoy fantastic dining options, entertainment and relaxing centres as you sail through different ports of call. Find P&O cruise deals on your P&O Cruises from Southampton sailing and book now for a fraction of the price. 

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Looking for the best cruise deals on P&O cruises from Southampton? Book your cruise deal online or contact us and our expert cruise concierges will help you find the perfect itinerary and best offer on your P&O cruises from Southampton.

Showing 30 out of 385 cruises
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DEPARTS FROM UK

Cruise From:
Was £7999pp Now: £7759pp

Epic South America Journey

Southampton | Las Palmas de Gran Canaria | Sao Vicente Island | Recife | Salvador de Bahia | Rio de Janeiro | Santos | Montevideo | Falkland Islands | Punta Arenas | Puerto Montt | San Antonio | Coquimbo | Arica | Callao | Fuerte Amador | Cartagena | Aruba | Curaçao | Saint George's | Bridgetown | Castries | Saint John's | Sint Maarten | Santa Cruz de Tenerife | Southampton

  • 03 Jan 2028
  • 75 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £7999pp Now: £7759pp
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Holiday ID: 049345

DEPARTS FROM UK

Cruise From:
Was £3999pp Now: £3879pp

Caribbean Winter Warmth

Southampton | Santa Cruz de Tenerife | Bridgetown | Martinique | Castries | Bonaire | Aruba | Saint George's | Saint Vincent | Saint John's | Saint Kitts | Sint Maarten | Tortola | Praia da Vitória | Southampton

  • 04 Jan 2028
  • 35 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £3999pp Now: £3879pp
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Holiday ID: 049220
Fly Cruise From:
Was £4229pp Now: £4099pp

Southampton to San Francisco

Southampton | Las Palmas de Gran Canaria | Bridgetown | Aruba | Manzanillo | San Diego | San Francisco

  • 06 Jan 2028
  • 23 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Fly Cruise From:
Was £4229pp Now: £4099pp
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Holiday ID: 049277

DEPARTS FROM UK

Cruise From:
Was £23839pp Now: £23123pp

Epic World Explorer

Southampton | Las Palmas de Gran Canaria | Bridgetown | Aruba | Manzanillo | San Diego | San Francisco | Honolulu | Nawiliwili | Apia | Suva | Auckland | Tauranga | Wellington | Sydney | Airlie Beach | Cairns | Rabaul | Busan | Nagasaki | Kagoshima | Tokyo | Hong Kong | Manila | Nha Trang | Laem Chabang | Singapore | Port Klang | Colombo | Male | Mauritius | Saint-Denis de la Réunion | Durban | Gqeberha (ex Port Elizabeth) | Cape Town | Walvis Bay | Sao Vicente Island | Santa Cruz de Tenerife | Southampton

  • 06 Jan 2028
  • 124 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Cruise From:
Was £23839pp Now: £23123pp
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Holiday ID: 049278

DEPARTS FROM UK

Cruise From:
Was £899pp Now: £872pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Lisbon | Vigo | La Coruña | Southampton

  • 08 Jan 2028
  • 14 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £71pp

Cruise From:
Was £899pp Now: £872pp
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Holiday ID: 049333

DEPARTS FROM UK

Cruise From:
Was £299pp Now: £290pp

Belgium and The Netherlands

Southampton | Zeebrugge | Southampton

  • 22 Jan 2028
  • 3 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £23pp

Cruise From:
Was £299pp Now: £290pp
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Holiday ID: 049334

DEPARTS FROM UK

Cruise From:
Was £899pp Now: £872pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 25 Jan 2028
  • 14 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £67pp

Cruise From:
Was £899pp Now: £872pp
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Holiday ID: 049335

DEPARTS FROM UK

Cruise From:
Was £999pp Now: £969pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 08 Feb 2028
  • 14 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £72pp

Cruise From:
Was £999pp Now: £969pp
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Holiday ID: 049221

DEPARTS FROM UK

Cruise From:
Was £349pp Now: £338pp

France

Southampton | Cherbourg | Le Havre | Southampton

  • 08 Feb 2028
  • 4 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £25pp

Cruise From:
Was £349pp Now: £338pp
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Holiday ID: 098871

DEPARTS FROM UK

Cruise From:
Was £649pp Now: £629pp

Northern Europe And Scandinavia

Southampton | Copenhagen | Oslo | Kristiansand | Southampton

  • 12 Feb 2028
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £46pp

Cruise From:
Was £649pp Now: £629pp
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Holiday ID: 098872

DEPARTS FROM UK

Cruise From:
Was £499pp Now: £484pp

Northern European City Escape

Southampton | Zeebrugge | Rotterdam | Hamburg | Southampton

  • 19 Feb 2028
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £35pp

Cruise From:
Was £499pp Now: £484pp
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Holiday ID: 098873

DEPARTS FROM UK

Cruise From:
Was £399pp Now: £387pp

Belgium and France

Southampton | Cherbourg | Le Havre | Zeebrugge | Southampton

  • 22 Feb 2028
  • 5 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £28pp

Cruise From:
Was £399pp Now: £387pp
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Holiday ID: 049222

DEPARTS FROM UK

Cruise From:
Was £379pp Now: £367pp

Rotterdam

Southampton | Rotterdam | Southampton

  • 26 Feb 2028
  • 4 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £26pp

Cruise From:
Was £379pp Now: £367pp
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Holiday ID: 098874

DEPARTS FROM UK

Cruise From:
Was £1779pp Now: £1725pp

Belgium and France

Southampton | Tangier | La Goulette | Valletta | Piraeus | Istanbul | Messina | Cádiz | Southampton

  • 27 Feb 2028
  • 21 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £121pp

Cruise From:
Was £1779pp Now: £1725pp
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Holiday ID: 049223

DEPARTS FROM UK

Cruise From:
Was £949pp Now: £920pp

Spain and Portugal

Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Lisbon | Vigo | La Coruña | Southampton

  • 01 Mar 2028
  • 14 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £65pp

Cruise From:
Was £949pp Now: £920pp
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Holiday ID: 049337

DEPARTS FROM UK

Cruise From:
Was £329pp Now: £319pp

Portugal and Canary Islands

Southampton | Zeebrugge | Southampton

  • 15 Mar 2028
  • 3 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £22pp

Cruise From:
Was £329pp Now: £319pp
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Holiday ID: 049338

DEPARTS FROM UK

Cruise From:
Was £999pp Now: £969pp

Spain, Portugal and Guernsey

Southampton | Copenhagen | Oslo | Kristiansand | Southampton

  • 18 Mar 2028
  • 7 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £65pp

Cruise From:
Was £999pp Now: £969pp
View cruise
Holiday ID: 049339

DEPARTS FROM UK

Cruise From:
Was £1249pp Now: £1211pp

Norway and Northern Lights

Southampton | Åndalsnes | Bodø | Tromsø | Haugesund | Southampton

  • 18 Mar 2028
  • 12 Nights
Limited time offer - Up to 10% booking discount is available exclusively to guests who have previously sailed with P&O
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £81pp

Cruise From:
Was £1249pp Now: £1211pp
View cruise
Holiday ID: 049346

DEPARTS FROM UK

Cruise From:
Was £1149pp Now: £1114pp

Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Lanzarote | Cádiz | Lisbon | Southampton

  • 19 Mar 2028
  • 14 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £75pp

Cruise From:
Was £1149pp Now: £1114pp
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Holiday ID: 049224

DEPARTS FROM UK

Cruise From:
Was £729pp Now: £707pp

Spain, France and Italy

Southampton | Bremerhaven | Amsterdam | Zeebrugge | Le Havre | Southampton

  • 25 Mar 2028
  • 7 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £47pp

Cruise From:
Was £729pp Now: £707pp
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Holiday ID: 049340

DEPARTS FROM UK

Cruise From:
Was £679pp Now: £658pp

Spain And France

Southampton | Getxo | La Coruña | Vigo | Cherbourg | Southampton

  • 26 Mar 2028
  • 7 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £44pp

Cruise From:
Was £679pp Now: £658pp
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Holiday ID: 081150

DEPARTS FROM UK

Cruise From:
Was £1399pp Now: £1357pp

Norwegian Fjords Spain And France

Southampton | Getxo | La Coruña | Vigo | Cherbourg | Southampton | Stavanger | Skjolden | Ålesund | Haugesund | Southampton

  • 26 Mar 2028
  • 14 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £89pp

Cruise From:
Was £1399pp Now: £1357pp
View cruise
Holiday ID: 081151

DEPARTS FROM UK

Cruise From:
Was £1249pp Now: £1211pp

Portugal, Caribbean and Azores

Southampton | Åndalsnes | Alta | Tromsø | Haugesund | Southampton

  • 30 Mar 2028
  • 12 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £79pp

Cruise From:
Was £1249pp Now: £1211pp
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Holiday ID: 049347

DEPARTS FROM UK

Cruise From:
Was £729pp Now: £707pp

Norwegian Fjords

Southampton | Stavanger | Olden | Ålesund | Haugesund | Southampton

  • 01 Apr 2028
  • 7 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £46pp

Cruise From:
Was £729pp Now: £707pp
View cruise
Holiday ID: 081108

DEPARTS FROM UK

Cruise From:
Was £1099pp Now: £1066pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 01 Apr 2028
  • 14 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £69pp

Cruise From:
Was £1099pp Now: £1066pp
View cruise
Holiday ID: 081206

DEPARTS FROM UK

Cruise From:
Was £1129pp Now: £1095pp

Portugal And Canary Islands

Southampton | Lisbon | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Funchal | Southampton

  • 02 Apr 2028
  • 12 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £71pp

Cruise From:
Was £1129pp Now: £1095pp
View cruise
Holiday ID: 081087

DEPARTS FROM UK

Cruise From:
Was £749pp Now: £726pp

Norwegian Fjords

Southampton | Stavanger | Skjolden | Ålesund | Haugesund | Southampton

  • 02 Apr 2028
  • 7 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £47pp

Cruise From:
Was £749pp Now: £726pp
View cruise
Holiday ID: 081152

DEPARTS FROM UK

Cruise From:
Was £1479pp Now: £1434pp

Norwegian Fjords Spain And France

Southampton | Stavanger | Skjolden | Ålesund | Haugesund | Southampton | Getxo | La Coruña | Vigo | Cherbourg | Southampton

  • 02 Apr 2028
  • 14 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £93pp

Cruise From:
Was £1479pp Now: £1434pp
View cruise
Holiday ID: 081153

DEPARTS FROM UK

Cruise From:
Was £779pp Now: £755pp

Norwegian Fjords

Southampton | Stavanger | Olden | Ålesund | Haugesund | Southampton

  • 08 Apr 2028
  • 7 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £48pp

Cruise From:
Was £779pp Now: £755pp
View cruise
Holiday ID: 081109

DEPARTS FROM UK

Cruise From:
Was £779pp Now: £755pp

Spain And France

Southampton | Getxo | La Coruña | Vigo | Cherbourg | Southampton

  • 09 Apr 2028
  • 7 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining

Interest free Monthly Payments from JUST £48pp

Cruise From:
Was £779pp Now: £755pp
View cruise
Holiday ID: 081154

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

Why Choose P&O Cruises From The UK

Southampton is home to the most popular departure port in the UK and is another port for you to explore before or after your cruise. Cruising from Southampton allows you to avoid the fees and hassle of airports to get an early start on your cruises from the UK . P&O cruises from Southampton are perfect for many cruisers since all you have to do is drive down to the port and board your cruise. Whether you are looking for the best cruises for families or venturing out as a couple with our adult only cruises, departing aboard a P&O Cruises from Southampton makes for a more convenient and affordable holiday. Sail hassle free by opting for our all-inclusive cruises. 

P&O Cruises from Southampton destinations 

P&O Cruises from Southampton sails to many amazing destinations. You can sail closer to home on an Europe Cruise and explore popular holiday countries like Spain, France and Portugal or you can see the beauty of the Northern lights on a Norwegian Fjords cruise. If you are looking for warmer climates to escape the cold, the Caribbean is calling with our P&O cruises to the Caribbean, South American Cruises, Mediterranean Cruises, Canaries Islands Cruises and more. P&O cruises from Southampton offers World Cruises where you can explore multiple countries and learn more about the world as you traverse through the continents. Whether you are looking to sail on short break cruises or venturing out with our long duration cruises, you will find P&O cruises from Southampton that will tick all your boxes. 

Book Your P&O Cruises From Southampton

Browse through our wide range of P&O cruises from Southampton with amazing itineraries. Looking to sail a few days or 3 months in the future? Our last minute cruise deals on 2026 cruises will allow you to save more on your cruise holiday. Take advantage of our early booking discounts and save your place onboard with our low deposits when you are sailing on 2027 Cruises or 2028 Cruises. Whenever you are looking to sail, we have exclusive cruise deals on P&O cruises from Southampton.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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