Princess Cruises in the Mediterranean

Discover all Princess Cruises in the Mediterranean available at Cruise118.com below. This stunning part of the world is home to popular cruise destinations including Barcelona, Santorini, Lisbon and more. When you set sail with Princess Cruises to the Mediterranean, you can enjoy the luxuries you would expect from the Princess Cruises fleet all while soaking up the sun and diverse cultures that the Mediterranean has to offer.

Princess Cruises to the Mediterranean also include a number of cruises from Southampton offering guests a hassle-free no-fly experience directly from the UK. Cruise only holidays can be booked directly online where you can take advantage of our Cruise118.com online booking discount. Those heading further afield can speak to our cruise concierge team who will be happy to package together flights, transfers, hotel stays and more.

Showing 30 out of 316 cruises
Per Person
Total Price
Fly Cruise From:
Was £1102pp Now: £1063pp

Civitavecchia | Corfu | Dubrovnik | Kotor | Naples | Civitavecchia

  • 06 Oct 2026
  • 7 Nights
Fly Cruise From:
Was £1102pp Now: £1063pp
View cruise
REF: PRINCESSN634
Cruise From:
Was £1739pp Now: £1678pp

Civitavecchia | Corfu | Dubrovnik | Kotor | Naples | Civitavecchia | Salerno | Santorini | Kusadasi | Katakolon | Civitavecchia

  • 06 Oct 2026
  • 14 Nights
Cruise From:
Was £1739pp Now: £1678pp
View cruise
REF: PRINCESSN634A
Cruise From:
Was £1049pp Now: £1012pp

Barcelona | Ibiza | Marseille | Ajaccio | Genoa | La Spezia | Civitavecchia

  • 10 Oct 2026
  • 7 Nights
Cruise From:
Was £1049pp Now: £1012pp
View cruise
REF: PRINCESSU640
Cruise From:
Was £1679pp Now: £1620pp

Barcelona | Ibiza | Marseille | Ajaccio | Genoa | La Spezia | Civitavecchia | Naples | Khania | Kusadasi | Mykonos | Athens

  • 10 Oct 2026
  • 14 Nights
Cruise From:
Was £1679pp Now: £1620pp
View cruise
REF: PRINCESSU640A
Cruise From:
Was £2369pp Now: £2286pp

Barcelona | Ibiza | Marseille | Ajaccio | Genoa | La Spezia | Civitavecchia | Naples | Khania | Kusadasi | Mykonos | Athens | Bar | Corfu | Messina | Naples | Barcelona

  • 10 Oct 2026
  • 21 Nights
Cruise From:
Was £2369pp Now: £2286pp
View cruise
REF: PRINCESSU640B
Fly Cruise From:
Was £996pp Now: £961pp

Civitavecchia | Salerno | Santorini | Kusadasi | Katakolon | Civitavecchia

  • 13 Oct 2026
  • 7 Nights
Fly Cruise From:
Was £996pp Now: £961pp
View cruise
REF: PRINCESSN635
Fly Cruise From:
Was £1036pp Now: £999pp

Civitavecchia | Naples | Khania | Kusadasi | Mykonos | Athens

  • 17 Oct 2026
  • 7 Nights
Fly Cruise From:
Was £1036pp Now: £999pp
View cruise
REF: PRINCESSU641
Fly Cruise From:
Was £1777pp Now: £1714pp

Civitavecchia | Naples | Khania | Kusadasi | Mykonos | Athens | Bar | Corfu | Messina | Naples | Barcelona

  • 17 Oct 2026
  • 14 Nights
Fly Cruise From:
Was £1777pp Now: £1714pp
View cruise
REF: PRINCESSU641A
Fly Cruise From:
Was £1528pp Now: £1474pp

Civitavecchia | Alghero | Genoa | Livorno | Valletta | Messina | Mykonos | Rhodes | Kusadasi | Athens

  • 20 Oct 2026
  • 11 Nights
Fly Cruise From:
Was £1528pp Now: £1474pp
View cruise
REF: PRINCESSN636N
Cruise From:
Was £2369pp Now: £2286pp

Civitavecchia | Alghero | Genoa | Livorno | Valletta | Messina | Mykonos | Rhodes | Kusadasi | Athens | Santorini | Khania | Katakolon | Corfu | Split | Dubrovnik | Kotor | Naples | Civitavecchia

  • 20 Oct 2026
  • 21 Nights
Cruise From:
Was £2369pp Now: £2286pp
View cruise
REF: PRINCESSN636B
Cruise From:
Was £2159pp Now: £2083pp

Southampton | Hamburg | Copenhagen | Skagen | Oslo | Rotterdam | Zeebrugge | Le Havre | Southampton | Isle of Portland | Vigo | Funchal | Santa Cruz de Tenerife | Port Canaveral

  • 24 Oct 2026
  • 27 Nights
Cruise From:
Was £2159pp Now: £2083pp
View cruise
REF: PRINCESSY631A
Cruise From:
Was £719pp Now: £693pp

Athens | Bar | Corfu | Messina | Naples | Barcelona

  • 24 Oct 2026
  • 7 Nights

Interest free Monthly Payments from JUST £214pp

Cruise From:
Was £719pp Now: £693pp
View cruise
REF: PRINCESSU642
Cruise From:
Was £1539pp Now: £1485pp

Athens | Bar | Corfu | Messina | Naples | Barcelona | Málaga | Gibraltar | Cádiz | Santa Cruz de Tenerife | Fort Lauderdale

  • 24 Oct 2026
  • 22 Nights
Cruise From:
Was £1539pp Now: £1485pp
View cruise
REF: PRINCESSU642A
Cruise From:
Was £859pp Now: £828pp

Barcelona | Málaga | Gibraltar | Cádiz | Santa Cruz de Tenerife | Fort Lauderdale

  • 31 Oct 2026
  • 15 Nights

Interest free Monthly Payments from JUST £236pp

Cruise From:
Was £859pp Now: £828pp
View cruise
REF: PRINCESSU643
Cruise From:
Was £3029pp Now: £2922pp

Athens | Kusadasi | Rhodes | Corfu | Kotor | Split | Dubrovnik | Siracuse | Valletta | Gibraltar | Casablanca | Las Palmas de Gran Canaria | Fort Lauderdale

  • 31 Oct 2026
  • 25 Nights
Cruise From:
Was £3029pp Now: £2922pp
View cruise
REF: PRINCESS2628B
Cruise From:
Was £1319pp Now: £1272pp

Athens | Santorini | Khania | Katakolon | Corfu | Split | Dubrovnik | Kotor | Naples | Civitavecchia

  • 31 Oct 2026
  • 10 Nights
Cruise From:
Was £1319pp Now: £1272pp
View cruise
REF: PRINCESSN637N

Cruise & Stay

France & Portugal Passage with Orlando Stay

Holiday prices from:
£1499pp

France & Portugal Passage with Orlando Stay

Southampton | Isle of Portland | Vigo | Funchal | Santa Cruz de Tenerife | Port Canaveral

  • 05 Nov 2026
  • 19 Nights
Holiday prices from:
£1499pp
Fly Cruise From:
£1399pp

Southampton | Isle of Portland | Vigo | Funchal | Santa Cruz de Tenerife | Port Canaveral

  • 05 Nov 2026
  • 15 Nights
Fly Cruise From:
£1399pp
View cruise
REF: PRINCESSY632
Fly Cruise From:
Was £1114pp Now: £1075pp

Civitavecchia | Salerno | Santorini | Kusadasi | Katakolon | Civitavecchia

  • 10 Nov 2026
  • 7 Nights
Fly Cruise From:
Was £1114pp Now: £1075pp
View cruise
REF: PRINCESSN639
Cruise From:
Was £1799pp Now: £1736pp

Civitavecchia | Salerno | Santorini | Kusadasi | Katakolon | Civitavecchia | Palma de Mallorca | Gibraltar | Casablanca | Santa Cruz de Tenerife | Santa Cruz de La Palma | Fort Lauderdale

  • 10 Nov 2026
  • 23 Nights
Cruise From:
Was £1799pp Now: £1736pp
View cruise
REF: PRINCESSN639A
Cruise From:
Was £1059pp Now: £1021pp

Civitavecchia | Palma de Mallorca | Gibraltar | Casablanca | Santa Cruz de Tenerife | Santa Cruz de La Palma | Fort Lauderdale

  • 17 Nov 2026
  • 16 Nights

Interest free Monthly Payments from JUST £246pp

Cruise From:
Was £1059pp Now: £1021pp
View cruise
REF: PRINCESSN640

Cruise & Stay

South American Passage with Buenos Aires Stay

Holiday prices from:
£2389pp

South American Passage with Buenos Aires Stay

Buenos Aires | Montevideo | Rio de Janeiro | Las Palmas de Gran Canaria | Arrecife | Santa Cruz de Tenerife | Casablanca | La Coruña | Southampton

  • 06 Feb 2027
  • 25 Nights
Holiday prices from:
£2389pp
Fly Cruise From:
£2169pp

Buenos Aires | Montevideo | Rio de Janeiro | Las Palmas de Gran Canaria | Arrecife | Santa Cruz de Tenerife | Casablanca | La Coruña | Southampton

  • 09 Feb 2027
  • 22 Nights
Fly Cruise From:
£2169pp
View cruise
REF: PRINCESS8714
Cruise From:
Was £4019pp Now: £3878pp

Buenos Aires | Montevideo | Rio de Janeiro | Las Palmas de Gran Canaria | Arrecife | Santa Cruz de Tenerife | Casablanca | La Coruña | Southampton | Ålesund | Trondheim | Tromsø | Alta | Molde | Southampton

  • 09 Feb 2027
  • 36 Nights
Cruise From:
Was £4019pp Now: £3878pp
View cruise
REF: PRINCESS8714A
Cruise From:
Was £899pp Now: £867pp

Port Canaveral | Kings Wharf | Ponta Delgada | Casablanca | La Coruña | Southampton

  • 07 Mar 2027
  • 15 Nights

Interest free Monthly Payments from JUST £104pp

Cruise From:
Was £899pp Now: £867pp
View cruise
REF: PRINCESSY711

DEPARTS FROM UK

Cruise From:
Was £659pp Now: £635pp

Southampton | La Coruña | Bilbao | Le Verdon-sur-Mer | Cherbourg | Southampton

  • 22 Mar 2027
  • 7 Nights

Interest free Monthly Payments from JUST £71pp

Cruise From:
Was £659pp Now: £635pp
View cruise
REF: PRINCESSY712
Cruise From:
Was £768pp Now: £741pp

Fort Lauderdale | Santa Cruz de Tenerife | Cartagena | Palma de Mallorca | Barcelona

  • 28 Mar 2027
  • 14 Nights

Interest free Monthly Payments from JUST £81pp

Cruise From:
Was £768pp Now: £741pp
View cruise
REF: PRINCESSU714
Cruise From:
Was £1660pp Now: £1599pp

Fort Lauderdale | Santa Cruz de Tenerife | Cartagena | Palma de Mallorca | Barcelona | Palma de Mallorca | Marseille | Ajaccio | Genoa | La Spezia | Civitavecchia

  • 28 Mar 2027
  • 21 Nights

Interest free Monthly Payments from JUST £174pp

Cruise From:
Was £1660pp Now: £1599pp
View cruise
REF: PRINCESSU714A

DEPARTS FROM UK

Cruise From:
Was £1373pp Now: £1324pp

Southampton | Cádiz | Barcelona | La Seyne-sur-Mer | Livorno | Civitavecchia | Ajaccio | Southampton

  • 29 Mar 2027
  • 14 Nights

Interest free Monthly Payments from JUST £144pp

Cruise From:
Was £1373pp Now: £1324pp
View cruise
REF: PRINCESSY713N
Fly Cruise From:
Was £1149pp Now: £1099pp

Barcelona | Palma de Mallorca | Marseille | Ajaccio | Genoa | La Spezia | Civitavecchia

  • 11 Apr 2027
  • 7 Nights

Interest free Monthly Payments from JUST £113pp

Fly Cruise From:
Was £1149pp Now: £1099pp
View cruise
REF: PRINCESSU715

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

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